• Hello. I took my 2 guinea pigs in because I thought they had a URI, which they both did. They were put on the medicine Enrofloxacin. I give them this 2 times a day. One of my piggies was improving, however today I noticed she is breathing shallower. The other biggie sounds the same, shallow and clogged up. I'm concerned if this medications are working or not.

    Hi Sabrina,
    Upper respiratory infections in Guinea Pigs can be very challenging to treat. Enrofloxacin is one of the strongest antibiotics we have available, but there are some organisms like mycoplasma that are still resistant. If they are not improving, and worsening, I do suggest that you bring them back for a follow-up.

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