How Much Will Vaccines Cost for My Puppy Pricing Variant Vaccine costs vary widely based on your location and whether they are administered by medical professionals during an examination or by others. Proper vaccination for your puppy or kitten is one of the most important investments in your pet's life long good health. Some people chose to purchase the least expensive products possible and administer them at home. The cheapest option is not always best. Almost anyone can follow the manufacturers' directions for administration. However, only qualified veterinary professionals can advise you on what is best for your pet, determine if your pet is healthy enough to safely receive vaccines, effectively and promptly treat possible reactions and diagnose and treat other health problems during examination. It is also important for vaccines to be shipped, stored and handled properly to be effective. Vaccines administered by a veterinarian are your best and safest option. Need more information or advice? Contact your nearest Banfield Pet Hospital to schedule an appointment today.